2. PROTAC
  3. PROTAC Linkers
  4. Dde Biotin-PEG4-alkyne

Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Dde Biotin-PEG4-alkyne 構造式

Dde Biotin-PEG4-alkyne 構造式

CAS 番号 : 1802908-00-4

容量 価格（税別） 在庫状況 数量
100 mg USD 350 在庫あり
250 mg USD 588 在庫あり
500 mg   お問い合わせ  
1 g   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

Dde Biotin-PEG4-alkyne 関連抗体

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PROTAC Linkers アイソフォーム固有の製品をすべて表示:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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製品説明

Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

PEGs

 

体外実験

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dde Biotin-PEG4-alkyne 関連抗体
分子量

650.83

分子式

C32H50N4O8S
CAS 番号
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C(NCCOCCOCCOCCOCC/C(NCC#C)=C1C(CC(C)(C)CC\1=O)=O)CCCC[C@H]2SC[C@@]([C@@]2([H])N3)([H])NC3=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
純度とドキュメンテーション
参考文献
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Dde Biotin-PEG4-alkyne Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dde Biotin-PEG4-alkyne1802908-00-4PROTAC LinkersInhibitorinhibitorinhibit

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製品名:
Dde Biotin-PEG4-alkyne
製品番号:
HY-140924
数量:
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