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Death receptor 5 (DR5), also known as TRAIL receptor 2 (TRAILR2) and tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), is a cell surface ...
Fas受容体は細胞表面に位置する細胞死受容体(英語版)であり、そのリガンドであるFasリガンド(FasL)が結合した場合にプログラム細胞死(アポトーシス)をもたらす。この経路は ...
FADD(Fas-associated protein with death domain)は、ヒトでは11番染色体(英語版)の11q13.3領域のFADD遺伝子によってコードされるタンパク質である。
The term death receptor refers to those members of the TNF receptor ... Death receptor 5 (10B), TRAILR2, CD262, TNFRSF10B · Decoy receptor 1 (10C) ...
"Death receptor 5, a new member of the TNFR family ... "Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5".
Death receptor 3 ... ), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation.
The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis) if it binds its ligand, Fas ligand (FasL).
Death receptor 6 ... ), is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the JNK and NF-κB pathways.
Conatumumab (originally AMG-655) is a monoclonal antibody developed for the treatment of cancer. It is a fully human monoclonal agonist antibody.
The death domain (DD) is a protein interaction module composed of a bundle of six alpha-helices. DD is a subclass of protein motif known as the death fold.