... proteins, and not just the heparan sulfate chains, may also play important roles in signal transduction. Syndecan-4, for example, can bind and activate protein kinase Cα (PKCα) following FGF2-induced oligomerization (399). The full ...
... Cα have been used to dramatically reduce the expression of this isozyme without affecting the expression of other isozymes, allowing the effects of protein kinase Cα on cellular adhesion to be studied. 6 ... Protein Kinase C 217.
... protein kinase C isotypes . J. Biol . Chem . , 270 , 22412-16 . 26 Cazaubon , S. , Webster , C. , Camoin , L. et al ... Cα . Biochem . J. , 301 , 443–8 . 29 Orr , J.W. and Newton , A.C. ( 1994 ) Requirement for negative charge on ...
... Protein kinase Cα protein kinase were activated with the protocol provided by the manufacture. The equal concentration of Protein kinase Cα in the purified 6xHis-taged hTERT frac- tions were subjected to incubation in appropriate ...
... rat osteoblast cells ( ROS 17 / 2.8 ) ABSTRACT We studied the role of PKCa in osteocalcin regulation 150 Chapter IV: The effect of protein kinase Cα overexpression osteocalcin gene expression in rat osteoblast cells (ROS 17/2 8)
... Cα (PKCα) is exquisitely sensitive to oxidant-induced S-glutathiolation, which fully and reversibly inactivates the kinase activity.4 The methods are likely to be broadly ... Protein Kinase C Isozyme Activity by S-Glutathiolation.
... protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport ... Cα inhibits insulin- stimulated tyrosine phosphorylation of insulin receptor substrate-1. Mol. Endo., 8, 51 ...
... protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function. The Journal of ... Cα in human Ntera 2 neurons (NT2N). Biochemistry, 39, 7428–7435. Jung, Y.-S., Lee, B. K., Park, H.-S., Shim, J. K. ...
... proteins Protein kinase Cα C2 -domain X-ray Ca2+-bound± phospholipids 2 n.d. 17 Protein kinase Cβ C2 -domain X-ray Ca2+-bound 3 n.d. 16 Protein kinase Cδ C2 -domain X-ray Ca2+-independent n.a. 23 Protein kinase Cε C2 -domain X-ray Ca2+- ...
... protein ( KIBRA ) and the exocyst complex and localize to the leading edge of moving cells , where they phosphorylate ( activate ) components of the MAPK module , such as Jun N - terminal kinase ... Protein Kinase-Cα (Conventional PKC)