The death domain (DD) superfamily comprising the death domain (DD) subfamily, the death effector domain (DED) subfamily, the caspase recruitment domain (CARD) ...

The death domain superfamily, composed of the death domain (DD), death effector domain (DED) and caspase recruitment domain (CARD) families of proteins ...

Procaspases are enormous prodomains that contain structural motifs from the so-called death domain superfamily. Death domains are 80 to 100-residues long ...

This superfamily represents the death domain and other structurally similar domains, including DED, CARD and the DAPIN domain.

The DD superfamily is one of the largest and most studied domain superfamilies. It currently comprises four subfamilies, the death domain (DD) subfamily, the ...

The death domain superfamily has emerged as the prime mediator of the interactions necessary for transducing a death signal. This superfamily consists of death ...

Definition. A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and ...

May 15, 2021 · Human death domain superfamily proteins (DDSPs) play important roles in many signaling pathways involved in cell death and inflammation.

Jan 2, 2007 · The unifying feature of the DD super- family is the six-helical bundle structural fold as first revealed by nuclear magnetic reso- nance (NMR) ...

The Death Domain (DD) superfamily, which is one of the largest classes of protein interaction modules, plays a pivotal role in apoptosis, inflammation, necrosis ...