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Death receptor 4 (DR4), also known as TRAIL receptor 1 (TRAILR1) and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), is a cell surface ...
Death receptors (DR) are cell surface receptors that belong to the tumor necrosis factor (TNF) receptors superfamily, and play a key role in apoptosis. DR4 ( ...
Death receptor 4 (DR4) is a cell surface receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and triggers apoptosis upon ligation ...
Death Receptor 4 (DR4) is a type of receptor that is involved in neural development and degeneration, with potential roles in neuroprotection in Parkinson's ...
death receptor 4 ... A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the ...
Sep 3, 2004 · In this report, we show that expression of DR4 from a strong CMV promoter efficiently kills breast cancer cells even in the absence of exogenous ...
Increased DR4 and DR5 expression increases TRAIL binding to its receptors. This leads to activation of caspase 8 by its recruitment to the receptor via FADD- ...
Recent studies demonstrated that death receptors DR4 and DR5 are constitutively localized to chromatin from the plasma membrane via clathrin-dependent ...
A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes · Abstract.
パスウェイの説明：. アポトーシスは、対応するリガンドによるFas、TNFαR、DR3、DR4、DR5などのデスレセプターの活性化によって誘導されます。デスレセプターリガンド ...
