eGFR (estimated Glomerular Filtration Rate) indicates how much the kidneys are able to excrete waste products in the blood into the urine, and the lower this ...

Mar 19, 2022 · Combination EGFR-TKI treatment may decrease tumor growth and prevent the development of resistant variants. This work created an experimental ...

Some studies have shown that epidermal growth factor receptor (EGFR) mutations can be heterogeneously distributed in individual tumors.

Jul 26, 2019 · Most EGFR mutations occur in somatic tumor tissue, with germline EGFR mutations being extremely rare. As a scarce example, the germline EGFR ...

Apr 16, 2021 · Approximately 15–30% of patients with lung cancer harbor mutations in the EGFR gene. Major EGFR mutations (>90% of EGFR-mutated lung cancer) ...

Oct 19, 2021 · Epidermal growth factor receptor (EGFR) plays a pivotal role in collective cell migration by mediating cell-to-cell propagation of ...

Apr 10, 2020 · The EGFR impact score can predict the responsiveness to TKI treatment in patients with EGFR mutant lung adenocarcinoma. Additionally, this ...

Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous ...

Mar 29, 2023 · In summary, this study suggested that the oncogenic EGFR signaling pathway suppresses intrinsic CXCL chemokine expression in EGFR-mt LA cells ...

May 14, 2022 · Enhanced EGFR activation is a mechanism of lenvatinib resistance. In this study, we found that only Hep3B cells were amenable to the creation of ...